A case of severe organophosphate poisoning used a high-dose atropine

Effectiveness of High Dose Pralidoxime for Treatment of Organophosphate Poisoning

Background: For effective treatment of organophosphate (OP) poisoning, development of a standardized protocol with flexible dose regimen for atropine and pralidoxime is an essential step. In this study, we aimed to assess the protocol devised in our setting; Bach Mai Hospital Poison Treatment Center, for treatment of OP poisoning that included a higher dose regimen of pralidoxime (2PAM). Method...

High dose atropine in organophosphorus poisoning.

Severe organophosphate poisoning in a neonate.

Organophosphates (OP) are widely used as insecticides. Accidental OP poisoning is reported world over. These compounds inhibit the enzyme acetyl-cholinesterase within the peripheral and central nervous system by phosphorylation of its esteratic site. The resultant accumulation of acetylcholine at the cholinergic receptor sites, leads to signs of cholinergic toxicity. Accidental OP sites, leads ...

Acute Organophosphate Poisoning Induced Extrapyramidal Syndrome: A Case Report

Background: Organophosphorus compound ingestion is one of the most common modes of deliberate self-harm in developing countries like India. Neurological complications are known in acute, intermediate and delayed phases following organophosphate poisoning. However, extrapyramidal manifestations are rarely reported. Case presentation: A 30-year-old male patient was brought...

Atropine or hyoscine in treatment of acute organophosphate poisoning?

The abdominal wall was infiltrated with lignocaine and incised in the mid-line. 3 litres of semisolid food was removed from the stomach and exploration revealed gross gaseous distension of small and large bowel, with infarction of the small bowel, and gas bubbles in the mesenteric veins. The ischaemic bowel was decompressed and packed with hot towels without any improvement and the patient died...